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Hexarelin 2mg*10vials 1kit

$135.00

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Hexarelin (HEX) is a peptide GH secretagogue with a potent ability to stimulate GH secretion and recently reported cardioprotective actions. Because Hexarelin’s amino acid sequence may help in promoting the body to produce more Growth Hormone, it will not shut down the body’s own production. Purity (HPLC) : 99% min. 5mg per vial

Molecular Formula : C47H58N12O6      Molecular Weight : 877.05      CAS No. : 140703-51-1

Sequence: His-2-Me-D-Trp-Ala-Trp-D-Phe-Lys-NH2

For RESEARCH PURPOSES ONLY


Hexarelin is a synthetic peptide composed of 6 amino acids making it a “hexaptide” with a structure that has been considered to promote the release of Growth Hormone. Research has shown that the effects from GH include increased bone mineral density, increased mitosis and meiosis which leads to more muscle mass, triglyceride hydrolysis which causes prominent fat loss, connective tissue strengthening, and improved skin elasticity. Because Hexarelin’s amino acid sequence may help in promoting the body to produce more Growth Hormone, it will not shut down the body’s own production. This is a very important factor and makes Hexarelin an attractive chain when compared to Growth Hormone alone.


For RESEARCH PURPOSES ONLY.


Hexarelin is a (GH)-releasing hexapeptide which belongs to the GHS family. This particular protein has been found to act on both pituitary gland and the hypothalamus, however, its mechanisms of action in the human physiologic system has not yet been fully elucidated (Arvat et al. 1995). This synthetic peptide has similar GH-secreting properties with its predecessors such as the GHRP-6, GHRP-2 and GHRP-1. Hexarelin is GHRP analog in which the Trp was substituted with chemically more table 2-Methyl-Trp (Denghenghi et al. 1994). The chemical structure of which is shown in the following:


Hexarelin Structure


Many studies on mice have been carried out geared towards deeper understanding of its chemical activity. Many research studies reported that some of its effects are increase in muscle strength and endurance, gain muscle mass, neural protection, rehabilitation of the joints and increased rate of wound healing. However, unlike GHRP-6, hexarelin does not induce food intake because of its incapability to drastically increase the grehlin levels that are responsible for the feeling of hunger and faster emptying of the gastric system. But the studies of Deghenghi et al. (1994) reported that hexarelin possessed similar effectiveness in stimulating the GH release in a long-lasting event and slightly more effective than the GHRP-6. These are supported by a number of studies. Locatelli et al. (1999) reported that hexarelin provides protection and healing especially for the cardiac dysfunction and abnormalities. They have observed that 7 days after the administration of the hexarelin to the rat, it prevented the exacerbation of the ischemia-reperfusion damage that has been induced by hypophysectomy. Furthermore, hexarelin also prevented the increase in diastolic pressure of the left ventricular end, so as with coronary perfusion pressure, reactivity of the coronary vasculature to angiotensin and release of the creatine kinase from the perfusate of the heart. Also, it was suggested that hexarelin prevented the fall in prostacyclin release and enhances recovery of contractility. It has also been noted that its mechanisms of action are not mediated by the growth hormone, but most probably because of the activation of specific receptors in the heart (Locatelli et al. 1999).

Hexarelin (HEX) is a peptide GH secretagogue with a potent ability to stimulate GH secretion and recently reported cardioprotective actions. However, hexarelin (HEXARELIN) effects in the brain are largely unknown, and the aim of the present study was to examine the potential protective effect of hexarelin (HEXARELIN) on the central nervous system after injury, as well as on caspase-3, Akt, and extracellular signal-regulated protein kinase (ERK) signaling cascades in a rat model of neonatal hypoxia-ischemia.



  • Model: Hexarelin 2mg 1kit
  • 499999 Units in Stock


This product was added to our catalog on Saturday 13 October, 2012.

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